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Control peptides can be used to ensure reproducibility in proteomics experiments conducted with PTMScan.
What if an antibody could identify a PTM, regardless of the flanking amino acid sequence? This innovative idea is the basis of CST's PTMScan product line.
CST PTMScan tutorial video explains how to use antibodies to quickly and efficiently enrich PTM peptides for mass spectrometry-based proteomics
PTMScan Motif Antibody Kits from Cell Signaling Technology
PTMScan® Glycosylation
PTMScan videos and links to complementary technologies for phospho-peptide enrichment and Science Webinar on Proteomics and Cell Signaling.
PTMScan Motif Antibodies and Kits, for customers who purchase a license and would like to perform PTMScan Proteomics in-house.
Overview of methodology and client deliverables for the PTMScan Direct Proteomic Service offered by Cell Signaling Technology.
Features, benefits, and product listing for PTMScan Direct Proteomic Services for the targeted screening of defined protein sites critical for drug and biomarker discovery.
Matthew Stokes, Ph.D., and Christopher Rose, Ph.D. introduce Cell Signaling Technology’s PTMScan® method and provide a demonstration of its applications.
Immunoaffinity purification of PTM peptides for mass spectrometry-based proteomics--PTMScan
Identifies and quantifies up to many hundreds of critical signaling nodes across pathways involved in cancer biology, immune cell signaling, and more.
Information and case study data for the PTMScan Direct Apoptosis/Autophagy Service offered by CST.
Information and case study data for the PTMScan Direct PI3K/Akt Service offered by CST, which allows for targeted screening of 105 proteins within the Akt pathway.
CST can identify and quantify thousands of post-translational modification sites specific to your sample—phosphorylation, ubiquitination, acetylation, and more.
A video tutorial illustrating the methodology behind PTMScan Technology and an example of its use in a recent phosphoproteomic study authored by scientists from CST.
PTMScan® Sumoylation Remnant Motif Kit - SUMOylation Proteomics
This video introduces PTMScan technology, a platform for the enrichment of post-translational modifications (PTMs) in mass spectrometry-based proteomics studies.
Learn about the history of Cell Signaling Technology and our commitment to providing reproducible tools to move your science forward.
Nov 2008, Renewal of a research agreement with Ortho-Biotech Oncology Research & Development, under which CST will employ its patented PhosphoScan® and PTMScan® technologies in research aimed at biomarker discovery and validation for multiple enzyme target classes and lead small-molecule inhibitors.
This video describes the simplified PTMScan® HS workflow for LC-MS analysis of ubiquitination and SUMOylation that improves readout sensitivity, reduces sample prep time, and eliminates lyophilization, 9M urea, and antibody elution steps.
Information and case study data for the PTMScan Direct Ser/Thr Kinases Service, which allows for the targeted screening of a defined set of protein modification sites.
Information and case study data for the PTMScan Direct Cell Cycle and DNA Damage Service offered by CST.
Whether your lab is well-versed and equipped to do Mass Spec analysis in house or your lab has never considered setting up a proteomics experiment before, the Proteomics group can help.
To study pathways regulated by nitrotyrosine, CST offers two recombinant monoclonal antibodies against the same PTM for WB and proteomic applications.
Learn how PTMScan technology facilitates translational discovery, identification of disease drivers, and development of markers and treatments, as exemplified in the study of non-small cell lung cancer (NSCLC).