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Ferroptosis is a form of programmed cell death characterized by condensed mitochondria, reduction in mitochondrial cristae, and increased membrane density.
It is very difficult to detect HIF-1alpha under normoxic conditions as the protein is quickly degraded. To see strong signal, it is necessary to induce the expression of the protein by either stressing the cells under hypoxic conditions or treating with a hydroxylase inhibitor such as cobalt chloride.
Humans have been creatively reusing materials for centuries. As our global waste problem grows, we must be more creative and diligent in finding solutions.
There are no tools or therapies to cure, prevent, or slow the progression of AD. Current therapeutic approaches include targeting amyloid plaques and neurofibrillary tangles.
Flow cytometry enables you to save time and analyze many characteristics of your cells in one experiment, using classic principles of antibody detection.
CST Technical Support Article
These synthetic peptides are recoverable using our immunoaffinity purification (IAP) antibody beads, and thus provide users with a measure of PTMScan success and reproducibility that is independent of sample preparation.
Expert-reviewed interactive pathway providing a current overview of Translational Control.
This is a four-part series featuring tips to improve your ChIP protocol.
Expert-reviewed interactive pathway providing a current overview of Regulation of eIF2.
Learn how enzymatic digestion can help you get better ChIP results.
Researchers combined their expertise to successfully pioneer a new path towards identifying the ubiquitous protein modification O-GlcNAcylation.
Expert-reviewed interactive pathway providing a current overview of Nuclear Receptor Signaling.
Interactive p38 MAPK pathway. Learn how p38 MAPK is involved in regulation of HSP27, MAPKAPK-2, MAPKAPK-3, & several transcription factors.
Expert-reviewed interactive pathway providing a current overview of TLR signaling.
Expert-reviewed interactive pathway providing a current overview of Regulation of Actin Dynamics.
A research timeline can demonstrate that you've considered project feasibility and future directions show that your plans span beyond the current proposal.
Student interns spent the summer in projects spanning the breadth of the company, learning science and the business via hands-on experience and mentoring.
Expert-reviewed interactive pathway providing a current overview of the Warburg Effect.
Even with new immunoassay technologies and methods, the foundation is still the antibody pair, whose specificity and sensitivity dictate assay performance.
Expert-reviewed interactive pathway providing a current overview of T Cell Receptor (TCR) Signaling.
Flow Cytometry Protocol for FoxP3 on Human Peripheral Blood Mononuclear Cells (PBMC): easy to follow directions describing the step by step experimental procedure.
Expert-reviewed interactive pathway providing a current overview of Regulation of Microtubule Dynamics.
Discover the TGF Beta signaling pathway and impact on cell growth & tissue homeostasis. Learn here the mechanisms behind this vital signaling cascade.
Co-staining with multiple antibodies is a low-content form of multiplex analysis that be achieved using different host species or fluorophore conjugates.